Research Article

Advanced Glycation End Products Induce Vascular Smooth Muscle Cell-Derived Foam Cell Formation and Transdifferentiate to a Macrophage-Like State

Table 2

Lipid levels in VSMC stimulated by different concentrations of CML.

TreatmentMouse VSMC cholesterol mass (μg/mg protein)
CE (% of TC)FCTC

No oxLDL (12.2%)
oxLDL-loaded
CMLNonea (36.6%)aa
1 μmol/l (41.5%)
10 μmol/lb (52.3%)b
100 μmol/lb (48.0%)bb

a, compared with the no oxLDL group, b, compared with the oxLDL-loaded group.