The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid

Table 3

Comparison of VEGF parameters between the experimental and control groups.

Parameter	Group		level
	Scleroderma ()	Control ()
Serum VEGF (pg/ml) ()	346.27 (399.88)	197.737 (155.04)	0.4705
Serum sVEGFR-2 (pg/ml) ()	10184.00 (2507.77)	9110.125 (2858.61)	0.0970
Serum VEGF/sVEGFR-2 ()	0.0775 (0.2373)	0.0350 (0.0752)	0.4081
VEGF in tears (pg/ml) ()	275.30 (552.39)	352.135 (135.25)	<0.001
sVEGFR-2 in tears (pg/ml) ()	87.25 (69.92)	8274.653 (11033.51)	<0.001
VEGF/sVEGFR-2 in tears ()	1.1305 (0.7295)	0.2391 (0.3418)	<0.001

Significant difference according to the Mann–Whitney test. Abbreviations: VEGF: vascular endothelial growth factor; sVEGFR-2: soluble form of vascular endothelial growth factor receptor 2; SD: standard deviation.