Research Article

Depression of lncRNA NEAT1 Antagonizes LPS-Evoked Acute Injury and Inflammatory Response in Alveolar Epithelial Cells via HMGB1-RAGE Signaling

Figure 3

NEAT1 suppression restrained LPS-evoked inflammation in A549 cells. After infection with LV-sh-NEAT1 or LV-sh-NC, A549 cells were exposed to LPS. (a) The mRNA levels of IL-6, IL-1β, and TNF-α were analyzed using a qRT-PCR assay (). (b) An ELISA was conducted to measure the production of IL-6, IL-1β, and TNF-α in supernatants of A549 cells (). vs. the control group. vs. the LPS-treated group.
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