Circulating Th1 and Th2 Subset Accumulation Kinetics in Septic Patients with Distinct Infection Sites: Pulmonary versus Nonpulmonary

Figure 4

Kinetics of Th1, Th2, and Th2/Th1 stratified by 28-day outcomes and Cox proportional hazards models in pulmonary and nonpulmonary sepsis. (a) Kinetics of Th1, Th2, and Th2/Th1 stratified by the 28-day outcome on D0, D3, and D7 in pulmonary and nonpulmonary sepsis. Data was presented as mean with mean squared error; values shown were determined by using the Mann-Whitney test: between 28-day survivors and nonsurvivors within the pulmonary sepsis group, ^# between 28-day survivors and nonsurvivors within the nonpulmonary sepsis group. (b) Death hazard ratios for severity scores, peripheral blood cell count, and T helper population within the study period in distinct subgroups. Significant risk factors are in red; factors without significance are in blue; significant protective factors are in green. APACHE = Acute Physiology and Chronic Health Evaluation; CCD = chronic cardiac dysfunction; SOFA = Sepsis-related Organ Failure Assessment; WBC = white blood cell; ALC = absolute lymphocyte count.

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