Ischemia/Reperfusion Injury: Pathophysiology, Current Clinical Management, and Potential Preventive Approaches

Figure 3

Immune-regulatory drugs could thwart destructive inflammation and promote tissue repair. Corticosteroids could enhance M2 differentiation while blocking NET, ROS, and granule-component deposition, thus blocking inflammatory damage. Also, azithromycin and rosuvastatin may induce cardioprotective leukocytes.