ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis

Figure 7

Using A-to-I editing, ADAR1 can reduce the maturation of miR-30a, upregulate SOCS3 expression, and then inhibit JAK/STAT3 signaling and reduce IL-6 and TNF-α expression.