Research Article

Intraoperative Peritoneal Interleukin-6 Concentration Changes in Relation to the High-Mobility Group Protein B1 and Heat Shock Protein 70 Levels in Children Undergoing Cholecystectomy

Table 1

Characteristics of the patients directed to cholecystectomy.

Study group () value

The type of surgical approachLaparoscopic () (62%)Open () (38%)

Gender (F/M)Male () (38%)
Female () (62%)
Male
() (35%)
Female
() (65%)
Male
() (43%)
Female
() (57%)

Age7-17 y (median, 13)
8-17 y (median, 12)7-17 y (median, 14)

Operation time0.5 h-3.5 h
Up to 1.0 h ()Up to 2.0 h ()
More than 1.0 h ()More than 2 h ()
Lasting about 2 h ()Lasting about 2 h ()

Type of anesthesiaGeneral anesthesia () (100%)

Blood loss (mL)NonsignificantNonsignificant

Intra-abdominal pressure12 mmHgN/A

Insufflation gasCO2N/A

Intraoperative complicationsNoneNone

Type and dosage of medicationAll patients after surgical approach received standard surgical care and postoperative treatment according to the standard treatment protocols of our clinic and after surgeries were given intravenous paracetamol

Length of hospitalization after surgery2-10 days ()
2-5 days () (100%)More than 5 days () (100%)

A value < 0.05 is considered to show a significant difference between groups. Warmed, humidified CO2 does not attenuate the early inflammatory cytokine response [39]. Paracetamol has no influence on inflammatory response. N/A: not applicable.