Research Article

Anti-Tn Monoclonal Antibody Ameliorates Hyperoxia-Induced Kidney Injury by Suppressing Oxidative Stress and Inflammation in Neonatal Mice

Table 1

Kidney injury scores of histological changes in the mice.

Glomerular injuryAcute tubular necrosisTubulointerstitial inflammatory infiltratesTotal score

RA + PBS0 (0-1)0 (0-1)0 (0-1)1 (0-3)
RA + anti-Tn0 (0-1)0 (0-1)0 (0-1)1 (0-3)
Hyperoxia + PBS2 (1-2)a2 (1-2)a1 (0-2)a5 (2-6)a
Hyperoxia + anti-Tn0 (0-1)b0 (0-1)b0 (0-1)c2 (0-3)b

Data are presented as median (range). a vs. RA + PBS and RA + anti-Tn groups; b vs. hyperoxia + PBS group; c vs. hyperoxia + PBS group.