High-Intensity Interval Training Improves Physical Function, Prevents Muscle Loss, and Modulates Macrophage-Mediated Inflammation in Skeletal Muscle of Cerebral Ischemic Mice

Figure 3

Exercise protocols of high-intensity interval training and moderate-intensity aerobic training. (a, b) Regimens of traditional moderate-intensity aerobic training and low volume high-intensity interval training. (c) Relative percentage (%) of resting blood lactate (mmol/L) at D28 normalized to the D1 (). (d) and (m/min) at D7 in each group (). (e) Relative percentage (%) of and at D28 normalized to the D1 (). (f) Example of lactatemia kinetic (raw data) before and after HIIT. Arrows indicate the lactate threshold. Values are expressed as the of the mean. and compared with the sham group; ^# and ^## compared with the MCAO group as determined by one-way ANOVA (Tukey’s multiple comparison test) for the data with normal distribution. The letters for no significance were not shown. Abbreviation: : speed associated with the lactate threshold; : maximal speed; D7: 7 days after cerebral ischemia; D28: 28 days after cerebral ischemia.

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