Dysregulation of Innate Lymphoid Cells in Patients with Active Rheumatoid Arthritis and Mice with Collagen-Induced Arthritis

Table 1

Characteristics of HCs, patients with stable RA, and patients with active RA.

Characteristics	HCs ()	RA patients ()
		Low diseases status (, )	Active disease status (, )
Mean age (years)
Sex ratio (male/female)	8/28	6/25	5/20
Diseases duration (years)	NA
RF positivity ( (%))	NA	26 (83.88%)	20 (80.00%)
Anti-CCP positivity ( (%))	NA	23 (74.19%)	17 (68.00%)
ESR (mm/h)	NA
CRP (mg/dL)	NA
Tender joints	NA
Swollen joints	NA
VAS score (0-100 mm)	NA
DAS 28 score (CRP)	NA
DAS 28 score (ESR)	NA
Treatment	NA	28 (90.32%)	19 (76.00%)
None ( (%))	NA	3 (9.68%)	6 (24.00%)
Steroid ( (%))	NA	9 (29.03%)	4 (16.00%)
NSAIDS ( (%))	NA	5 (16.13%)	5 (20.00%)
DMARDS ( (%))	NA	27 (87.10%)	13 (52.00%)
TNF-α antagonist ( (%))	NA	9 (29.03%)	2 (8.00%)

Values ( or (%)) were compared using the unpaired Student’s -test or Fisher’s exact test. HCs: healthy controls; RA: rheumatoid arthritis; DAS28: disease activity score for 28 joints; RF: rheumatoid factor; anti-CCP: anticyclic-citrullinated peptide antibodies; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; VAS: visual analogue scale score for pain; NSAIDS: nonsteroidal anti-inflammatory drugs; DMARDs: disease-modifying antirheumatic drugs; TNF-α: tumor necrosis factor-α; NA: not available.