Salivary Biomarkers (Opiorphin, Cortisol, Amylase, and IgA) Related to Age, Sex, and Stress Perception in a Prospective Cohort of Healthy Schoolchildren
Table 3
The covariance models (ANCOVA) testing effect of interaction between clinical factors and salivary parameters.
Variable
Model 1 (sIgA)
Model 2 (sAA)
Model 3 (cortisol)
Model 4 (OPI)
value
value
value
value
(1) Age: group 1 (age 6-7) and group 2 (age 8-11)
10.964
0.001
2.057
0.152
0.032
0.858
0.170
0.681
(2) Sex: boys and girls
1.770
0.184
0.218
0.641
0.430
0.512
0.337
0.562
(3) BMI: normal and abnormal
1.929
0.166
2.468
0.117
3.996
0.046
0.063
0.802
(4) Stressful experiences: SE1(yes) and SE0 (no)
2.246
0.135
0.856
0.356
0.660
0.417
0.004
0.952
1.735
0.188
0.579
0.447
0.597
0.440
0.234
0.629
1.191
0.276
0.413
0.521
0.046
0.831
0.232
0.631
0.007
0.935
2.090
0.149
0.195
0.659
0.035
0.851
0.001
0.977
0.000
1.000
0.943
0.332
3.122
0.078
0.519
0.472
0.109
0.742
0.507
0.477
0.063
0.803
0.837
0.361
1.699
0.193
0.478
0.490
0.924
0.337
0.723
0.396
3.679
0.056
1.252
0.264
0.020
0.889
2.958
0.086
0.861
0.354
0.169
0.681
0.187
0.666
0.428
0.513
0.131
0.718
1.246
0.265
0.055
0.814
1.196
0.275
0.000
0.987
2.501
0.115
0.789
0.375
2.020
0.156
0.714
0.399
3.208
0.074
0.646
0.422
sIgA: salivary IgA; sAA: salivary alpha-amylase; OPI: opiorphin; SE1: children with distressing events in the past; SE0: children without distressing events in the past; BMI: body mass index. Significant value effect was marked (); body mass index (BMI) cut-offs were adopted by the International Obesity Task Force (IOTF).