Research Article

Salivary Biomarkers (Opiorphin, Cortisol, Amylase, and IgA) Related to Age, Sex, and Stress Perception in a Prospective Cohort of Healthy Schoolchildren

Table 3

The covariance models (ANCOVA) testing effect of interaction between clinical factors and salivary parameters.

VariableModel 1 (sIgA)Model 2 (sAA)Model 3 (cortisol)Model 4 (OPI)
value value value value

(1) Age: group 1 (age 6-7) and group 2 (age 8-11)10.9640.0012.0570.1520.0320.8580.1700.681
(2) Sex: boys and girls1.7700.1840.2180.6410.4300.5120.3370.562
(3) BMI: normal and abnormal1.9290.1662.4680.1173.9960.0460.0630.802
(4) Stressful experiences: SE1(yes) and SE0 (no)2.2460.1350.8560.3560.6600.4170.0040.952
1.7350.1880.5790.4470.5970.4400.2340.629
1.1910.2760.4130.5210.0460.8310.2320.631
0.0070.9352.0900.1490.1950.6590.0350.851
0.0010.9770.0001.0000.9430.3323.1220.078
0.5190.4720.1090.7420.5070.4770.0630.803
0.8370.3611.6990.1930.4780.4900.9240.337
0.7230.3963.6790.0561.2520.2640.0200.889
2.9580.0860.8610.3540.1690.6810.1870.666
0.4280.5130.1310.7181.2460.2650.0550.814
1.1960.2750.0000.9872.5010.1150.7890.375
2.0200.1560.7140.3993.2080.0740.6460.422

sIgA: salivary IgA; sAA: salivary alpha-amylase; OPI: opiorphin; SE1: children with distressing events in the past; SE0: children without distressing events in the past; BMI: body mass index. Significant value effect was marked (); body mass index (BMI) cut-offs were adopted by the International Obesity Task Force (IOTF).