Research Article

Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion

Table 1

Standard for clinical score of mice with iNKT infusion.

CriteriaGrade 0Grade 1Grade 2

Weight loss<10%>10% to <25%>25%
PostureNormalOnly lift the spine while stretching the bodyThe spine has been bulging heavily
ActivityNormalMild to moderate reductionOnly stimulation can activate
Fur textureNormalMild to moderate wrinklesSeverely wrinkled or sparse
Skin integrityNormalScales on claws or tailObvious skin peeling