Research Article

Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study

Table 2

Comparison of the predictive performance of different models in optimal feature subset in validation set.

VariableLR (95% CI)QDA (95% CI)NB (95% CI)SVM (95% CI)AdaBoost (95% CI)BP (95% CI) value

SEN65.4% (55.2-74.5%)a,c,d,e83.2% (75.7-90.6%)b81.2% (73.4-88.9%)b71.3% (62.3-80.3%)80.2% (72.3-88.1%)b83.2% (75.7-90.6%)b0.008
SPE90.0% (85.4-93.6%)77.4% (71.5-82.4%)78.3% (72.4-83.2%)83.9% (78.6-88.3%)80.4% (75.3-85.6%)76.5% (71.0-82.0%)0.002
FPR10.0% (6.4-14.9%)22.6% (17.6-28.5%)21.7% (16.8-27.6%)16.1% (11.7-21.4%)19.57% (14.4-24.7%)23.5% (18.0-29.0%)0.002
FNR35.6% (25.5-46.8%)a,c,d,e16.8% (9.4-24.3%)b9.1% (11.1-26.6%)b28.7% (10.7-37.7%)19.8% (11.9-27.7%)b26.8% (9.4-24.3%)b0.008
PPV73.3% (64.0-82.6%)61.3% (53.1-69.6%)a61.7% (53.3-70.0%)b,c65.5% (56.4-74.5%)a64.3% (55.8-72.8%)60.9% (52.6-69.1%)0.437
NPV85.5% (81.0-90.0%)91.2% (87.2-95.3%)90.4% (86.3-94.5%)86.9% (82.4-91.4%)90.2% (86.1-94.3%)91.2% (87.2-95.2%)0.239
Accuracy82.2% (78.0-86.3%)78.9% (74.4-83.3%)78.9% (74.4-83.3%)79.8% (75.4-81.4%)80.4% (76.1-84.7%)78.5% (74.1-83.0%)0.862
AUC0.840 (0.796-0.878)0.865 (0.824-0.900)0.864 (0.823-0.899)0.839 (0.795-0.877)0.863 (0.821-0.898)0.862 (0.820-0.897)/

aCompared with QDA, ; bCompared with LR, ; cCompared with NB, ; dCompared with AdaBoost, ; eCompared with BP, . value denoted the overall statistical result for the four models.