Research Article

Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study

Table 3

Comparison of the predictive performance of different models in optimal feature subset in test set.

VariableLR (95%CI)QDA (95%CI)NB (95%CI)SVM (95%CI)Adaboost (95%CI)BP (95%CI) value

SEN58.54% (42.20%-73.30%)60.98% (44.54%-75.38%)73.17% (56.69%-85.25%)60.98% (44.54%-75.38%)80.49% (64.63%-90.63%)75.61% (59.36%-87.09%)0.15
SPE93.33% (84.47%-95.52%)a,c,d,e86.67% (76.39%-93.08%)d76.00% (64.50%-84.79%)b89.33% (79.54%-94.95%)d73.33% (61.66%-82.58%)a,b,f74.67% (63.08%-83.69%)a,b0.001
FPR6.67% (1.02%-12.32%)a,c,d,e13.33% (5.64%-21.03%) d24.00% (14.33%-33.67%) b10.67% (3.68%-17.66%) d26.67% (16.66%-36.67%) a,b,f25.33% (15.49%-35.17%) a,b0.001
FNR41.46% (26.38%-56.54%)39.02% (24.09%-77.80%)26.83% (13.27%-40.39%)39.02% (24.09%-77.80%)19.51% (7.38%-31.64%)24.39% (11.25%-37.53%)0.15
PPV82.76% (63.51%-93.47%)71.43% (53.48%-84.76%)62.50% (47.33%-75.68%)75.76% (57.37%-88.26%)62.26% (47.87%-74.88%)62.00% (47.16%-75.00%)0.281
NPV93.33% (84.47%-97.52%)80.25% (69.61%-87.95%)83.82% (72.47%-91.27%)80.72% (70.29%-88.25%)87.30% (75.96%-93.97%)84.85% (73.44%-92.11%)0.87
Accuracy80.3% (73.0-87.7%)78.5% (71.1-85.9%)75.0% (67.0-83.0%)79.3% (71.8-86.8%)75.9% (68.0-83.8%)75.0% (67.0-83.0%)0.831
AUC0.782 (0.694-0.853)0.785 (0.686-0.848)0.779 (0.688-0.849)0.772 (0.679-0.842)0.826 (0.740-0.888)0.805 (0.714-0.869)/

aCompared with QDA, ; bCompared with LR, ; cCompared with NB, ; dCompared with AdaBoost, ; eCompared with BP, ; fCompared with SVM, . value denoted the overall statistical result for the four models.