Research Article
Correlation of Low Levels of α-1 Antitrypsin and Elevation of Neutrophil to Lymphocyte Ratio with Higher Mortality in Severe COVID-19 Patients
Table 1
Clinical and laboratory analyses of the patients and differences in patients’ characteristics between NLR downward trend and NLR upward trend groups.
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Abbreviations: OR: odds ratio; NLR: neutrophil-lymphocyte ratio; AAT: alpha-1 antitrypsin; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; PLT: platelet; RBC: red blood cells; O2sat: arterial oxygen saturation; BS: random blood sugar; SGOT: serum glutamic oxaloacetic transaminase; SGPT: serum glutamic pyruvic transaminase. Normal range: AAT: 90-200 mg/dl; CRP: >10 mg/l; RBC: 3.8-5.8 106/μl; PLT: 150-450 103/μl; O2sat: 95-99%; BS: up to 140 mg/dl; SGOT: up to 41 U/l; SGPT: up to 41 U/l; troponin: <0.04 ng/ml. Note: data are shown as , median with interquartile range (IQR), and number (%). Independent-samples -test or Mann-Whitney was used for continuous variables with the normal and nonnormal distribution, respectively. The chi-square test and Fisher’s exact or Fisher-Freeman-Halton test were used for categorical variables. #NLR upward trend group consisted of individuals with having an upward NLR trend along with those with no NLR change during the study. |