Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway

Figure 1

PLE exerted anti-inflammation effect in allergic asthma in vivo. (a) Representative images showing pathological changes in lung tissues determined by H&E staining (magnification, ×100). (b) The scores of inflammatory cell infiltration in lung tissues ( independent slices from three mice of each group). (c) WBC, LYM, MONO, NEUT, and EOS counts in BALF (). (d–g) The level of IL-6, TNF-α, and IL-4 and the ratio of IL-4/IFN-γ in BALF (). (h–k) The concentration of IgE, IgG1, IgG2a, and IgG2b in serum (). ^##vs. the control group; and vs. the model group.

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