Research Article
Perilla Leaf Extract Attenuates Asthma Airway Inflammation by Blocking the Syk Pathway
Figure 3
Effects of PLE on the expressions and phosphorylation of Syk and its downstream signaling molecules in vivo. (a) The representative photomicrographs (×200), (b) percentage of positively stained cells, and (c) mean integrated optical density (MOD) of Syk staining ( independent slices from three mice in each group). (d) Representative photomicrographs (×200), (e) percentage of positively stained cells, and (f) MOD of p-Syk staining ( independent slices from three mice in each group). The expression of (g) Syk, (h) p-Syk, (i) PKC, (j) p-PKC, (k) p65, (l) p-p65, (m) cPLA2, and (n) p-cPLA2 in OVA-induced asthma mouse lung tissues was determined by WB (). ##vs. the control group; and vs. the model group.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |
(i) |
(j) |
(k) |
(l) |
(m) |
(n) |