IL-9 and IL-10 Single-Nucleotide Variants and Serum Levels in Age-Related Macular Degeneration in the Caucasian Population

Table 8

Serum IL-10 levels in relation to the genotypes.

Model		Early AMD (pg/ml), median (IQR)	value	Exudative AMD (pg/ml), median (IQR)	value	Atrophic AMD (pg/ml), median (IQR)	value	Control group (pg/ml), median (IQR)	value
IL-10 rs1800871
Dominant	GA+AA vs. GG	9.2 (15.8) vs. 9.1 (1.5)	0.571	8.6 (3.9) vs. 7.7 (2.6)	0.312	9.3 (1.1) vs. 9.5 (2.2)	0.230	8.7 (2.6) vs. 8.8 (3.9)	0.442
Recessive	AA vs. GA+GG	(-) vs. 9.2 (1.4)	—	(-) vs. 7.9 (2.9)	—	(-) vs. 9.4 (1.6)	—	(-) vs. 8.8 (2.9)	—
IL-10 rs1800872
Dominant	GT+TT vs. GG	9.2 (15.8) vs. 9.1 (1.5)	0.571	8.6 (3.9) vs. 7.7 (2.6)	0.312	9.3 (1.1) vs. 9.5 (2.2)	0.230	8.7 (2.6) vs. 8.8 (3.9)	0.442
Recessive	TT vs. GT+GG	(-) vs. 9.2 (1.4)	—	(-) vs. 7.9 (2.9)	—	(-) vs. 9.4 (1.6)	—	(-) vs. 8.8 (2.9)	—
IL-10 rs1800896
Dominant	TC+CC vs. TT	9.1 (1.8) vs. 9.3 (7.8)	0.800	7.2 (2.3) vs. 9.3 (1.4)	0.048	9.4 (2.2) vs. 9.3 (0.7)	0.800	8.8 (3.4) vs. 8.7 (-)	0.573
Recessive	CC vs. TC+TT	9.2 (-) vs. 9.1 (2.7)	0.546	6.7 (2.2) vs. 8.5 (2.5)	0.054	8.7 (1.5) vs. 9.5 (1.2)	0.153	8.7 (-) vs. 8.8 (2)	0.958

Only two genotypes were determined.