Research Article

Metformin and Probiotics Interplay in Amelioration of Ethanol-Induced Oxidative Stress and Inflammatory Response in an In Vitro and In Vivo Model of Hepatic Injury

Figure 3

Probiotic V and Met alone or in combination regulates the lipid accumulation in the liver to prevent ethanol-induced hepatic injury. Histological examination of liver sections stained with hematoxylin and eosin (100x magnification) of (a) control, (b) ethanol-fed, (c) Met (75 mg/kg)+ethanol-fed, (d) probiotic V (108 CFU/day)+ethanol-fed, and (e) probiotic V (108 CFU/day)+Met (75 mg/kg)+ethanol-fed rats.
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