IL-1β Impaired Diabetic Wound Healing by Regulating MMP-2 and MMP-9 through the p38 Pathway

Figure 3

Diabetic wounds display elevated MMP expression and reduced TIMP expression: (a) mRNA levels of MMP2, MMP9, TIMP1, and TIMP2 in nondiabetic and diabetic wound tissues from patients evaluated by qPCR; (b) mRNA levels of MMP2, MMP9, TIMP1, and TIMP2 in control and db/db wound tissues from mice; (c) protein expression of MMP2, MMP9, TIMP1, and TIMP2 in nondiabetic and diabetic wounds evaluated by western blot; (d, e) mRNA quantification (d) and protein expression (e) in nFB and dFB samples. .

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