Research Article

A Cornflower Extract Containing N-Feruloylserotonin Reduces Inflammation in Human Skin by Neutralizing CCL17 and CCL22 and Inhibiting COX-2 and 5-LOX

Figure 10

5-LOX enzymatic inhibition: endogenous 5-LOX enzymatic activity in THP-1 cells differentiated in macrophages (PMA). Macrophages pretreated with CFEM or N-FS (N-feruloylserotonin) for 1 hour. 5-LOX induction (IL-3) with the test substance for 24 hours. One-way ANOVA: ; .