UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer

Figure 1

UBC was upregulated in prostate cancer tissues and cells. In prostate cancer tissues and paracancerous tissue, (a) IHC was used to detect ubiquitin-protein (UBC) expression. vs. paracancerous tissues;  μm, the magnification is 400 times;  μm, the magnification is 100 times. (b, c) qRT-PCR and WB were performed to detect ubiquitin-encoding gene UBA52, UBA80, UBB, and UBC expression. vs. paracancerous tissues. In prostate cell line RWPE-1 and prostate cancer cell lines PC3, CWR22, VCAP, and DU145, (d) ICC were used to detect ubiquitin-protein expression. vs. the control group (prostate cell line RWPE-1);  μm, the magnification is 400 times;  μm, the magnification is 100 times. (e, f) qRT-PCR and WB detected ubiquitin-encoding gene UBA52, UBA80, UBB, and UBC expression. vs. the control group (prostate cell line RWPE-1).

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