Research Article

Effect of Garlic Organic Sulfides on Gene Expression Profiling in HepG2 Cells and Its Biological Function Analysis by Ingenuity Pathway Analysis System and Bio-Plex-Based Assays

Table 5

DSs regulate the expression of genes related to cell proliferation and apoptosis.

Gene symbolGene titleFoldChange

F2RL2Coagulation factor II (thrombin) receptor-like 214.14Up
15.28
15.01
HSPA1A///HSPA1BHeat shock 70 kDa protein 1A///heat shock 70 kDa protein 1B4.29Up
4.30
3.68
GCLCGlutamate-cysteine ligase, catalytic subunit2.32Up
2.51
2.49
GCLMGlutamate-cysteine ligase, modifier subunit2.29Up
2.40
2.48
SLC2A2Solute carrier family 2 (facilitated glucose transporter), member 22.17Down
3.24
3.01
TLR6Toll-like receptor 62.11Up
2.34
2.05
FOSv-fos FBJ murine osteosarcoma viral oncogene homolog3.16Up
3.88
4.14
SOCS1Suppressor of cytokine signaling 12.07Down
2.68
2.08
NCF2Neutrophil cytosolic factor 2 (65 kDa, chronic granulomatous disease, autosomal 2)4.29Up
3.12
3.16
VDRVitamin D (1,25-dihydroxyvitamin D3) receptor2.06Down
2.69
2.86
SPP1Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)3.20Up
2.64
2.82
FOSL1FOS-like antigen 12.19Up
2.39
2.34
JAG1Jagged 1 (Alagille syndrome)2.76Up
3.59
4.01