Research Article
Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors
Table 4
Clinical characteristics of patients randomized to EMiC2 and AV1000S at baseline.
| Characteristics | EMiC2 () | AV1000S () |
| Age (years) | (26-81) | (26-89) | Gender, male | 6 (43%) | 13 (81%) | SAPS III | (48-85) | (45-107) | TISS | (30-57) | (26-48) | Leukocyte count (×103/μl) | (2-34) | (2-35) | Nonsurvivors | 8 (57.1%) | 9 (56.3%) | Comorbidities, number (% of total) | Cardiovascular | 8 (57%) | 10 (63%) | Pulmonary | 1 (7%) | 6 (38%) | Hepatitis/pancreatitis | 1 (7%) | 0 (0%) | Neurological | 6 (43%) | 3 (19%) | Renal | 1 (7%) | 4 (25%) | Diabetes | 3 (21%) | 6 (38%) | Primary site of infection, number (% of total) | Lung | 1 (7%) | 0 (0%) | Abdomen | 5 (36%) | 5 (31%) | Blood | 3 (21%) | 4 (25%) | Urinary tract | 1 (7%) | 2 (13%) | Other | 3 (21%) | 4 (25%) | Unknown | 1 (7%) | 1 (6%) |
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Data are represented as (range) or (%). SAPS III: Simplified Acute Physiology Score III; TISS: Therapeutic Intervention Scoring System. . |