Research Article

Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors

Table 4

Clinical characteristics of patients randomized to EMiC2 and AV1000S at baseline.

CharacteristicsEMiC2 ()AV1000S ()

Age (years) (26-81) (26-89)
Gender, male6 (43%)13 (81%)
SAPS III (48-85) (45-107)
TISS (30-57) (26-48)
Leukocyte count (×103/μl) (2-34) (2-35)
Nonsurvivors8 (57.1%)9 (56.3%)
Comorbidities, number (% of total)
 Cardiovascular8 (57%)10 (63%)
 Pulmonary1 (7%)6 (38%)
 Hepatitis/pancreatitis1 (7%)0 (0%)
 Neurological6 (43%)3 (19%)
 Renal1 (7%)4 (25%)
 Diabetes3 (21%)6 (38%)
Primary site of infection, number (% of total)
 Lung1 (7%)0 (0%)
 Abdomen5 (36%)5 (31%)
 Blood3 (21%)4 (25%)
 Urinary tract1 (7%)2 (13%)
 Other3 (21%)4 (25%)
 Unknown1 (7%)1 (6%)

Data are represented as (range) or (%). SAPS III: Simplified Acute Physiology Score III; TISS: Therapeutic Intervention Scoring System. .