Research Article

Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic-Treated Mice

Figure 5

Butyrate treatment decreases the CD14+ monocyte/macrophage population but increases the CD19+ B cell population in bone marrow following osteotomy. Immunophenotyping of single-cell suspensions from bone marrow (BM), inguinal lymph node (iLN), and spleen from operated mice was performed. (a) Percent of viable CD45+ CD14+ monocytes/macrophages, (b) CD45+ CD19+ B cells, (c) CD45+ CD3+ CD4+ T cells, and (d) CD45+ CD3+ CD8+ T cells in spleen, iLN, and BM, in the absence and presence of butyrate and , respectively. Data shown are . .
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