Recombinant Human Thymosin Beta-4 Protects against Mouse Coronavirus Infection

Figure 1

Process of mice experiment. Each of the mice in the sham group was intraperitoneally injected with 0.1 mL of normal saline (NS) daily from days 0 to 10. The mice in the placebo group were each intraperitoneally injected with TCID₅₀ of MHV-A59 on day 0, and 0.1 mL NS was intraperitoneally injected into each mouse once daily from days 1 to 10. The mice in the rhTβ4 group were intraperitoneally injected with TCID₅₀ of MHV-A59 per mouse on day 0, and 300 μg of rhTβ4 in 0.1 mL NS was intraperitoneally injected per mouse daily from days 1 to 10. The mice in each group were observed until day 14.