The lncRNA H19/miR-766-3p/S1PR3 Axis Contributes to the Hyperproliferation of Keratinocytes and Skin Inflammation in Psoriasis via the AKT/mTOR Pathway

Figure 2

Proliferative and inflammatory effects of miR-766-3p on HaCaT cells. (a-c) HaCaT cells were transfected with miR-766-3p mimics/NC and inhibitor/NC; miR-766-3p expressions were detected with qRT-PCR (a); proliferative effects were assessed by CCK-8 (b-c). (d-e) HaCaT cells were treated with M5; ELISA showed the expression level of IL-17A (d) and IL-22 (e). Data were shown as the mean ± SD, P <0.05, P<0.01, P<0.001. All the experiments were repeated at least three times.

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