Review Article

Galectin-3: A Novel Marker for the Prediction of Stroke Incidence and Clinical Prognosis

Table 2

Association of plasma Gal-3 levels with stroke outcomes.

Ischemic stroke

Dong et al. [46]OutcomeSensitivitySpecificityCut-off value
Functional outcome88.4%76.9%53.5 pg/mL
Wang et al. [63]OutcomeQ1Q2Q3Q4
Death or major disability (OR)1.001.091.161.55
Death (OR)1.000.740.812.10
Major disability (OR)1.001.131.191.43
Haemorrhagic stroke
Yan et al. ([64])1-week mortality73.3%79.4%28.9 ng/mL
6-month mortality90.9%64.6%22.4 ng/mL
6-month unfavourable outcome89.5%65.5%18.9 ng/mL
Liu et al. ([62])6-month mortality77.8%70.6%24.6 ng/mL
6-month unfavourable outcome81.1%77.1%23.4 ng/mL

Wang et al. categorized their study participants into 4 subgroups according to the quartiles of Gal-3 levels with Q4 being the highest quartile and Q1 being the lowest one. OR indicates odds ratio.