Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Table 3

Preoperative and postoperative hematological parameters.

	Before surgery	Post-CPB			value
		4 h	24 h	48 h
White blood cell count (K/μL)	11.04; (7.14-12.21)	14.06; (11.02-17.66)^†	14.17; (11.86-18.09)^†	14.75; (12.13-20.19)^†	<0.001
Lymphocytes (K/μL)	4.66; (3.66-7.76)	1.70; (1.02-2.41)^†	1.87; (1.22-2.23)^†	2.37; (1.51-2.98)^†	<0.001
Neutrophils (K/μL)	3.33; (2.00-4.91)	10.59; (8.28-13.86)^†	10.64; (8.35-13.66)^†	10.97; (7.61-15.29)^†	<0.001
Neutrophil to lymphocyte ratio	0.57; (0.35-1.05)	6.83; (4.06-10.88)^†	5.92; (4.28-9.25)^†	5.07; (2.94-9.13)^†	<0.001
Monocytes (K/μL)	0.71; (0.50-1.04)	1.03; (0.73-1.48)^†	1.47; (0.86-1.93)^†	1.34; (0.85-1.81)^†	<0.001
Platelets (K/μL)	329; (272-390)	141; (118-170)^†	136; (110-164)^†	138; (107-178)^†	<0.001
Mean platelet volume (fL)	9.50; (9.00-10.00)	9.40; (8.80-9.90)	10.05; (9.45-10.40)^‡	10.30; (9.75-10.70)^‡	<0.001
C-reactive protein (mg/L)	2.07; (1.17-4.57)	2.88; (1.78-3.76)	69.50; (53.80-81.80)^†	136.19; (108.24-201.06)^†	<0.001

Variables are presented as median with interquartile range. Friedman test. † and ‡, respectively, and versus baseline (post hoc multiple comparisons). CPB: cardiopulmonary bypass.