Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
Table 3
Preoperative and postoperative hematological parameters.
Before surgery
Post-CPB
value
4 h
24 h
48 h
White blood cell count (K/μL)
11.04 (7.14-12.21)
14.06 (11.02-17.66)†
14.17 (11.86-18.09)†
14.75 (12.13-20.19)†
<0.001
Lymphocytes (K/μL)
4.66 (3.66-7.76)
1.70 (1.02-2.41)†
1.87 (1.22-2.23)†
2.37 (1.51-2.98)†
<0.001
Neutrophils (K/μL)
3.33 (2.00-4.91)
10.59 (8.28-13.86)†
10.64 (8.35-13.66)†
10.97 (7.61-15.29)†
<0.001
Neutrophil to lymphocyte ratio
0.57 (0.35-1.05)
6.83 (4.06-10.88)†
5.92 (4.28-9.25)†
5.07 (2.94-9.13)†
<0.001
Monocytes (K/μL)
0.71 (0.50-1.04)
1.03 (0.73-1.48)†
1.47 (0.86-1.93)†
1.34 (0.85-1.81)†
<0.001
Platelets (K/μL)
329 (272-390)
141 (118-170)†
136 (110-164)†
138 (107-178)†
<0.001
Mean platelet volume (fL)
9.50 (9.00-10.00)
9.40 (8.80-9.90)
10.05 (9.45-10.40)‡
10.30 (9.75-10.70)‡
<0.001
C-reactive protein (mg/L)
2.07 (1.17-4.57)
2.88 (1.78-3.76)
69.50 (53.80-81.80)†
136.19 (108.24-201.06)†
<0.001
Variables are presented as median with interquartile range. Friedman test. † and ‡, respectively, and versus baseline (post hoc multiple comparisons). CPB: cardiopulmonary bypass.