Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Figure 3

Pep-B ameliorated LPS-induced LDH release and oxidative stress in hDPSCs. Cells were treated with LPS (1 μg/ml) in the presence or absence of Pep-B (2.5, 5 μg/ml) for 24 h. (a) The LDH released was determined using a commercial kit. (b) Intracellular ROS was determined by DCFH-DA staining. (c) The stained images were quantified by fluorescence density from different group. , , ##, represents comparison with the control group, # represents comparison with the LPS group. Scale bars: 100 μm.

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