Sexual Effect of Platelet-to-Lymphocyte Ratio in Predicting Cardiovascular Mortality of Peritoneal Dialysis Patients

Table 3

Associations of PLR with all-cause and CVD mortality in univariate and multivariate Cox regression models.

Variable	All-cause mortality unadjusted model		Multivariate model		Cardiovascular mortality unadjusted model		Multivariate model
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
Age (y)	1.063 (1.056-1.071)	<0.001	1.056 (1.047-1.065)	<0.001	1.065 (1.054-1.076)	<0.001	1.054 (1.041-1.068)	<0.001
Gender (female, , %)
Female	0.978 (0.804-1.191)	0.826	1.001 (0.817-1.226)	0.995	0.877 (0.661-1.166)	0.367	0.863 (0.640-1.163)	0.333
Male	Ref.		Ref.		Ref.		Ref.
History of CVD (yes/no)
Yes	2.771 (2.242-3.425)	<0.001	1.373 (1.089-1.731)	0.007	3.341 (2.496-4.471)	<0.001	1.655 (1.200-2.282)	0.002
No	Ref.		Ref.		Ref.		Ref.
Diabetes (yes/no)
Yes	3.299 (2.706-4.021)	<0.001	1.650 (1.327-2.051)	<0.001	3.911 (2.959-5.171)	<0.001	1.999 (1.460-2.737)	<0.001
No	Ref.		Ref.		Ref.		Ref.
HGB (g/L)	0.990 (0.985-0.994)	<0.001	0.990 (0.985-0.996)	<0.001	0.991 (0.984-0.997)	0.006	0.990 (0.982-0.998)	0.015
ALB (g/L)	0.913 (0.895-0.932)	<0.001	0.972 (0.950-0.996)	0.020	0.927 (0.901-0.955)	<0.001	0.994 (0.960-1.029)	0.730
eGFR (mL/min/1.73 m^2)	1.022 (1.013-1.031)	<0.001	1.017 (1.003-1.032)	0.020	1.018 (1.003-1.034)	0.017	1.000 (0.963-1.039)	0.999
PLR	1.001 (1.000-1.003)	0.005	1.000 (0.999-1.001)	0.594	1.002 (1.001-1.004)	0.002	1.001 (0.999-1.002)	0.250
Platelet inhibitor (yes/no)
Yes	1.811 (1.301-2.520)	<0.001	0.893 (0.628-1.270)	0.529	2.077 (1.333-3.236)	0.001	0.936 (0.583-1.503)	0.784
No	Ref.		Ref.		Ref.		Ref.
β-Blockers
(yes/no)
Yes	0.683 (0.560-0.833)	<0.001	0.850 (0.692-1.044)	0.121	0.714 (0.538-0.946)	0.019	0.862 (0.644-1.153)	0.316
No	Ref.		Ref.		Ref.		Ref.

All the models were adjusted for age, gender, history of CVD, diabetic status, hemoglobin, serum albumin, estimated glomerular filtration rate, platelet inhibitor, and β-blockers. Abbreviations: PLR: the platelet-to-lymphocyte ratio; CVD: cardiovascular disease; HGB: hemoglobin; ALB: serum albumin; PLR: the platelet-to-lymphocyte ratio; eGFR: estimated glomerular filtration rate.