Research Article

The Dopamine D1 Receptor Attenuates Titanium Particle-Induced Inhibition of Osteogenesis by Activating the Wnt Signaling Pathway

Figure 6

D1R activation alleviates titanium particle-induced osteolysis in vivo. (a) Representative 3D μCT images of the mouse skull in the sham group, model group, D1R agonist group, and D1R inhibitor group. (b–e) Bone mineral density (BMD, in g/mm3) and comparative analysis of bone structural parameters, such as the ratio of bone volume to total volume (BV/TV, in %), ratio of bone surface to bone volume (BS/BV, in 1/mm), and ratio of bone surface to total volume (BS/TV, in 1/mm). Note: per group; vs. the model group.