A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling

<div>(a) Intraoral image after 4 weeks of natural healing after tooth extraction. (b) Intraoral image after the implant socket preparation during implant implantation. (c) The custom-made Ti–6AL–4 V screw-type implant. (d) 4-0 prelated silk wires before implant implantation.</div>

Mediators of Inflammation

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Figure 2: A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling 

Figure 2 | A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling 