Research Article
TLR4 Enhances Cerebral Ischemia/Reperfusion Injury via Regulating NLRP3 Inflammasome and Autophagy
Figure 4
TLR4 knockdown suppresses rises in NLRP3 and LC3 in H/R-induced SH-SY5Y cells. (a) TLR4 mRNA level. (b) NLRP3 mRNA level. (c) LC3 mRNA level. (d) protein expression level. (e) The ratio of TLR4 to β-actin. (f) The ratio of NLRP3 to β-actin. (g) The ratio of LC3-I to LC3-II. The data expressed as . +TLR4 siRNA: cells treated with siRNA against TLR4 (100 nm); +NC siRNA: cells with negative control siRNA (100 nm). vs. control; # vs. H/R; ## vs. H/R; ### vs. H/R.
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