Mediators of Inflammation

Biomarkers in Rheumatoid Arthritis


Publishing date
14 Mar 2014
Status
Published
Submission deadline
25 Oct 2013

Lead Editor

1Rheumatology Department, Amiens University Hospital and Inserm U 4666, University Picardy-Jules Verne, 80054 Amiens, France

2Institute of Molecular Medicine, Section Musculoskeletal Disease and Head of Translational Research in Immune Mediated Inflammatory Diseases, University of Leeds, Leeds, UK

3Rheumatology Department, Amiens University Hospital and Inserm U1088, University Picardy-Jules Verne, 80000 Amiens, France

4Hôpitaux Universitaires de Strasbourg, 67091 Strasbourg Cedex , France


Biomarkers in Rheumatoid Arthritis

Description

Rheumatoid arthritis (RA) leads to irreversible structural damage to joints, and it is critical to achieve a rapid suppression of inflammation in order to minimize disease associated damages. The best mean to achieve this goal is diagnosis and treatment as early as possible. RA's prevalence is estimated to be about 0.5% in most European populations, and it is therefore the most frequent chronic autoimmune inflammatory rheumatism.

The early clinical presentation of RA is very heterogeneous hence difficult to diagnose. Moreover, the current classification criteria for RA are not often fulfilled in the early stages of the disease. Furthermore, determining the outcome of a treatment in RA patients is also sometimes difficult to assess and currently relies on subjective scoring. Finally, when remission is achieved, it remains important to predict safe discontinuity of treatment allowing to maintain sustained remission and to reduce cost of expensive therapies such as biologics.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to characterise biomarkers in RA that may be useful in diagnosis and/or prognosis and may predict the response to treatments (DMARDs, biologics).

Potential topics include, but are not limited to:

  • Cytokines as early biomarkers
  • Bone biomarkers
  • New autoantibodies specificities
  • Carbamylation of antigens
  • Targets of anticitrullinated antibodies
  • Synovial markers
  • Genetic markers/gene expression
  • Cardiovascular risk markers
  • Proteomic markers
  • Predictors of response to biologics treatment

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/bmra/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 379310
  • - Editorial

Biomarkers in Rheumatoid Arthritis

Vincent Goëb | Patrice Fardellone | ... | Frédérique Ponchel
  • Special Issue
  • - Volume 2014
  • - Article ID 484280
  • - Review Article

Bone Remodelling Markers in Rheumatoid Arthritis

Patrice Fardellone | Alice Séjourné | ... | Vincent Goëb
  • Special Issue
  • - Volume 2014
  • - Article ID 834831
  • - Research Article

A Polymorphism of ORAI1 rs7135617, Is Associated with Susceptibility to Rheumatoid Arthritis

Jeng-Hsien Yen | Che-Mai Chang | ... | Wei-Chiao Chang
  • Special Issue
  • - Volume 2014
  • - Article ID 425068
  • - Review Article

Adipokines as Potential Biomarkers in Rheumatoid Arthritis

Annalisa Del Prete | Valentina Salvi | Silvano Sozzani
  • Special Issue
  • - Volume 2014
  • - Article ID 492873
  • - Review Article

Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis

Agata N. Burska | Laura Hunt | ... | Frederique Ponchel
  • Special Issue
  • - Volume 2014
  • - Article ID 342524
  • - Clinical Study

Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis

Isabelle Duroux-Richard | Yves-Marie Pers | ... | Florence Apparailly
  • Special Issue
  • - Volume 2014
  • - Article ID 643406
  • - Research Article

TLR2 Elicits IL-17-Mediated RANKL Expression, IL-17, and OPG Production in Neutrophils from Arthritic Mice

Viktoriya Milanova | Nina Ivanovska | Petya Dimitrova
  • Special Issue
  • - Volume 2014
  • - Article ID 537324
  • - Review Article

Could Biomarkers of Bone, Cartilage or Synovium Turnover Be Used for Relapse Prediction in Rheumatoid Arthritis Patients?

Delphine Dénarié | Elodie Constant | ... | Hubert Marotte
  • Special Issue
  • - Volume 2014
  • - Article ID 545493
  • - Review Article

Cytokines as Biomarkers in Rheumatoid Arthritis

Agata Burska | Marjorie Boissinot | Frederique Ponchel
Mediators of Inflammation
 Journal metrics
Acceptance rate41%
Submission to final decision77 days
Acceptance to publication36 days
CiteScore3.570
Impact Factor3.545
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