Mediators of Inflammation

Mediators of Neuroinflammation


Publishing date
20 Sep 2013
Status
Published
Submission deadline
03 May 2013

Lead Editor

1Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA

2Axis of Neurosciences, Laval University Hospital Research Center, 2705 Laurier boulevard, room T2-50, Quebec City, QC, Canada G1V 4G2

3Division of Comparative Pathology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA

4Neuropharmacology Laboratory, Indian Institute of Integrative Medicine (CSIR), Sanat Nagar, Srinagar 190005, India


Mediators of Neuroinflammation

Description

The understanding that neuroinflammation contributes to neurodegeneration and possibly to an autoimmune disease state is emerging in a growing number of nervous system pathologies such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, demyelinating polyradiculoneuropathies and peripheral neuropathies, Guillain-Barré syndrome, prion disease, depression and psychiatric disorders, stroke, and gliomas as well as for microbial infections such as NeuroAIDS, viral and bacterial encephalitis.

Although some inflammatory stimuli induce beneficial effects that help to limit disease, uncontrolled inflammation may result in the production of neurotoxic factors that amplify underlying disease states. Learning more about how inflammatory responses are induced within the nervous system will aid in designing safe and effective therapies for reversing or slowing the course of disease. We invite investigators to contribute original research articles and review articles that will help to expand the current knowledge of the specific mediators of neuroinflammation including inducers, sensors, transducers, amplifiers, and effectors of neuroinflammation. Potential areas include, but are not limited to:

  • Inducers and sensors of infection (pathogen-associated molecular signals, pattern recognition receptors, purinergic receptors, and scavenger receptors)
  • Inflammasome signaling at the heart of neuroinflammation
  • Transduction systems and regulators of neuroinflammation (signal adaptor proteins, transcription factors, and mitogen-activated protein kinase kinases)
  • Amplifiers and effectors of inflammation (cytokines, chemokines, and their receptors)
  • Role of prostaglandins and cyclooxygenases
  • Mediators of oxidative stress
  • Matrix metalloproteinases
  • Signaling that alters the integrity of the blood-brain barrier
  • Soluble molecules that alter neuroglial, neuron-neuron, and neurovascular communications
  • Autoimmunity, obesity, stress, and ageing
  • Environmental factors

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/neuroi according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 314261
  • - Editorial

Mediators of Neuroinflammation

Geeta Ramesh | Mario T. Philipp | ... | Muzamil Ahmad
  • Special Issue
  • - Volume 2013
  • - Article ID 432623
  • - Research Article

Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B

Xingyong Chen | Xiaogeng Shi | ... | Ruxun Huang
  • Special Issue
  • - Volume 2013
  • - Article ID 736085
  • - Research Article

Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Su Zhang | Quan-Cheng Kan | ... | Lin Zhu
  • Special Issue
  • - Volume 2013
  • - Article ID 480739
  • - Review Article

Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain

Geeta Ramesh | Andrew G. MacLean | Mario T. Philipp
  • Special Issue
  • - Volume 2013
  • - Article ID 172351
  • - Review Article

MicroRNAs as Novel Regulators of Neuroinflammation

Dominika Justyna Ksiazek-Winiarek | Magdalena Justyna Kacperska | Andrzej Glabinski
  • Special Issue
  • - Volume 2013
  • - Article ID 321460
  • - Research Article

Sildenafil (Viagra) Protective Effects on Neuroinflammation: The Role of iNOS/NO System in an Inflammatory Demyelination Model

Catarina Raposo | Ana Karolina de Santana Nunes | ... | Christina Alves Peixoto
  • Special Issue
  • - Volume 2013
  • - Article ID 701970
  • - Review Article

Development and Treatments of Inflammatory Cells and Cytokines in Spinal Cord Ischemia-Reperfusion Injury

Ping Zhu | Jia-xin Li | ... | Xiao-Kang Li
  • Special Issue
  • - Volume 2013
  • - Article ID 124614
  • - Review Article

TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion

Ying Wang | Pengfei Ge | Yuhong Zhu
  • Special Issue
  • - Volume 2013
  • - Article ID 963748
  • - Review Article

Role of Regulatory T Cells in Pathogenesis and Biological Therapy of Multiple Sclerosis

Milan Buc
  • Special Issue
  • - Volume 2013
  • - Article ID 615745
  • - Clinical Study

Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease

Yuan Sun | Xue Song Yin | ... | Li Jun Chi
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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