Mediators of Inflammation

Sphingolipids in Inflammation: From Bench to Bedside


Publishing date
01 Jan 2016
Status
Published
Submission deadline
14 Aug 2015

1Tohoku University, Sendai, Japan

2Juntendo University, Tokyo, Japan

3Stony Brook University, Stony Brook, USA

4University of Milano, Milano, Italy


Sphingolipids in Inflammation: From Bench to Bedside

Description

This special issue highlights the areas of research where sphingolipids are involved in inflammation. Inflammatory response is closely associated with generation and/or progression of diseases including cancer, cardiovascular diseases, diabetes, infectious diseases, neurodegenerative diseases, rheumatoid arthritis, and sphingolipidosis. In recent years, it has become apparent that sphingolipids, such as ceramide, ceramide-1-phosphate, lactosylceramide, and sphingosine-1-phosphate, are involved in inflammatory process. Therefore, uncovering the mechanisms by which sphingolipids regulate inflammatory processes could promote the development of novel therapies against health problem.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the pathobiology of sphingolipids in inflammation and provide valuable mechanistic insight that may translate to therapeutic opportunities. This special issue covers basic research, bioinformatic research, translational research, and (pre)clinical research.

Potential topics include, but are not limited to:

  • Sphingolipid metabolism and pathobiology in inflammation
  • Sphingolipids-based therapy in inflammatory diseases
  • Sphingolipid receptors
  • Therapeutics targeting of sphingolipid metabolism or signaling

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 7602526
  • - Editorial

Sphingolipids in Inflammation: From Bench to Bedside

Kazuyuki Kitatani | Kazuhisa Iwabuchi | ... | Laura Riboni
  • Special Issue
  • - Volume 2016
  • - Article ID 8606878
  • - Review Article

Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential

Masayo Aoki | Hiroaki Aoki | ... | Kazuaki Takabe
  • Special Issue
  • - Volume 2016
  • - Article ID 1503206
  • - Research Article

Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2

Alena Chumanevich | Piper Wedman | Carole A. Oskeritzian
  • Special Issue
  • - Volume 2016
  • - Article ID 3827684
  • - Review Article

Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces

Loubna Abdel Hadi | Clara Di Vito | Laura Riboni
  • Special Issue
  • - Volume 2015
  • - Article ID 487508
  • - Review Article

Role of Sphingolipids in the Pathobiology of Lung Inflammation

Riccardo Ghidoni | Anna Caretti | Paola Signorelli
  • Special Issue
  • - Volume 2015
  • - Article ID 640540
  • - Review Article

Sphingolipids as Regulators of the Phagocytic Response to Fungal Infections

Arielle M. Bryan | Maurizio Del Poeta | Chiara Luberto
  • Special Issue
  • - Volume 2015
  • - Article ID 520618
  • - Review Article

Sphingolipids in High Fat Diet and Obesity-Related Diseases

Songhwa Choi | Ashley J. Snider
  • Special Issue
  • - Volume 2015
  • - Article ID 120748
  • - Review Article

Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans

Kazuhisa Iwabuchi | Hitoshi Nakayama | ... | Kenji Takamori
  • Special Issue
  • - Volume 2015
  • - Article ID 831059
  • - Review Article

Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation

Shailaja Mahajan-Thakur | Andreas Böhm | ... | Bernhard H. Rauch
  • Special Issue
  • - Volume 2015
  • - Article ID 492659
  • - Research Article

Exogenous S1P Exposure Potentiates Ischemic Stroke Damage That Is Reduced Possibly by Inhibiting S1P Receptor Signaling

Eunjung Moon | Jeong Eun Han | ... | Jerold Chun
Mediators of Inflammation
 Journal metrics
Acceptance rate35%
Submission to final decision77 days
Acceptance to publication30 days
CiteScore3.570
Impact Factor3.545
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