Mediators of Inflammation

Mediators of Inflammation as Targets for Chronic Pain Treatment


Publishing date
24 May 2013
Status
Published
Submission deadline
04 Jan 2013

1University of Ljubljana, Faculty of Medicine, Department of Pharmacology and Experimental Toxicology, Korytkova 2, 1000 Ljubljana, Slovenia

2Medical University of Sofia, Department of Pharmacology, 1143 Sofia, Bulgaria

3The Hebrew University, Department of Cell and Developmental Biology, 91904 Jerusalem, Israel

4School of Medical Sciences, University of New South Wales, Sydney, NSW 2052 Australia

5University of Siena, Department of Physiology, Pain and Stress Neurophysiology Lab., Via Also Moro 2, 53100 Siena, Italy


Mediators of Inflammation as Targets for Chronic Pain Treatment

Description

The management of chronic pain represents an unsolved problem in clinical practice. A common underlying mechanism of a chronic pain is the presence of inflammation at the site of the damaged or affected tissue. The release of proinflammatory and immunoactive substances such as cytokines, neurotrophic factors, and chemokines initiates local actions and can result in a more generalized immune response that leads to the chronic pain condition. Recent studies indicate a strong communication between the immune, endocrine, and nervous system, including microglial and astroglial cells, in the maintenance of chronic pain. The knowledge of the signalling pathways between them is crucial to identify new therapeutic targets and offer new therapeutic possibilities in the threatment of chronic pain.

Articles for this special issue should be a continuation of present research trends and should focus on current knowledge of the role of mediators of inflammation in chronic pain, particularly molecular mechanisms, signalling molecules, and their role in the initiation and maintenance of chronic pain, as well as the interactions between inflammatory mediators and immune, endocrine, and nerve system. Potential topics include, but are not limited to:

  • Molecular pathways of chronic pain
  • Mediators of inflammation in neuropathic pain
  • Mediators of inflammation in cancer pain
  • Neuroinflammation and chronic pain
  • Endocrine system and chronic pain
  • The role of microglia in chronic pain
  • The role of astrocytes in chronic pain
  • Neuronal-glial interactions in chronic pain
  • Signalling pathways as a target for the treatment of chronic pain
  • Pharmacogenomics and the management of chronic pain

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/pain/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 783235
  • - Editorial

Mediators of Inflammation as Targets for Chronic Pain Treatment

Metoda Lipnik-Stangelj
  • Special Issue
  • - Volume 2013
  • - Article ID 979748
  • - Research Article

Cytokine Patterns in Brain Tumour Progression

Radu Albulescu | Elena Codrici | ... | Cristiana Pistol Tanase
  • Special Issue
  • - Volume 2013
  • - Article ID 950947
  • - Research Article

Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia

Carolina Muscoli | Concetta Dagostino | ... | Daniela Salvemini
  • Special Issue
  • - Volume 2013
  • - Article ID 905360
  • - Research Article

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats

Lorenzo Di Cesare Mannelli | Daniele Bani | ... | Paola Failli
  • Special Issue
  • - Volume 2013
  • - Article ID 648268
  • - Review Article

Neurovascular Unit in Chronic Pain

Beatrice Mihaela Radu | Placido Bramanti | ... | Paolo Francesco Fabene
  • Special Issue
  • - Volume 2013
  • - Article ID 864319
  • - Review Article

Pharmacogenetics of Chronic Pain and Its Treatment

Svatopluk Světlík | Karolína Hronová | ... | Ondřej Slanař
  • Special Issue
  • - Volume 2013
  • - Article ID 298326
  • - Review Article

Neuropathic Pain in Animal Models of Nervous System Autoimmune Diseases

David H. Tian | Chamini J. Perera | Gila Moalem-Taylor
  • Special Issue
  • - Volume 2013
  • - Article ID 340473
  • - Research Article

Chronic Pain Treatment: The Influence of Tricyclic Antidepressants on Serotonin Release and Uptake in Mast Cells

Ilonka Ferjan | Metoda Lipnik-Štangelj
  • Special Issue
  • - Volume 2013
  • - Article ID 183041
  • - Review Article

Testosterone-Induced Effects on Lipids and Inflammation

Stella Vodo | Nicoletta Bechi | ... | Anna Maria Aloisi
  • Special Issue
  • - Volume 2013
  • - Article ID 915189
  • - Research Article

Inflammatory Pain and Corticosterone Response in Infant Rats: Effect of 5-HT1A Agonist Buspirone Prior to Gestational Stress

Irina P. Butkevich | Viktor A. Mikhailenko | ... | Vladimir A. Otellin
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.400
Journal Citation Indicator0.610
Impact Factor4.711
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