Mediators of Inflammation

Inflammation in Sleep Debt and Sleep Disorders


Publishing date
19 Dec 2014
Status
Published
Submission deadline
01 Aug 2014

1Department of Pediatrics, University of Chicago, Chicago, IL, USA

2University Grenoble Alpes, Inserm, HP2 (ou U1042), 38041 Grenoble, France


Inflammation in Sleep Debt and Sleep Disorders

Description

Sleep is not only an essential physiological function but also serves important roles in promoting growth, maturation, and overall health. There is increasing interest regarding the impact of sleep and its disorders on the regulation of inflammatory processes and end-organ morbidities, particularly in the context of neurocognitive, metabolic, and cardiovascular diseases and their complications. Furthermore, jet lag and other perturbations of the circadian clock have also been linked to the regulation of fundamental regulatory properties underlying metabolic homeostasis. Sleep disorders such as obstructive sleep apnea syndrome (OSAS), a highly prevalent health problem across the age spectrum, are epidemiologically and mechanistically linked to metabolic deregulation. In the last decade, the emergence of increasing obesity rates has further led to remarkable increases in the prevalence of OSAS, along with more prominent neurocognitive, behavioral, cardiovascular, and metabolic morbidities.

Although the underlying mechanisms leading to OSAS-induced morbidities are likely multifactorial and remain to be fully elucidated, activation of inflammatory pathways by OSAS has emerged as an important pathophysiological component of the end-organ injury associated with this disorder. To this effect, it would appear that OSAS could be viewed as a chronic, low-grade inflammatory disorder. Furthermore, the concurrent presence of obesity and OSAS poses a theoretically increased risk of OSAS-related complications.

We invite submission of original research papers or structured and up-to-date comprehensive reviews. Potential topics include, but are not limited to:

  • The association and mechanisms linking sleep, experimental sleep manipulation, or sleep disorders and inflammatory processes and their downstream effects on end-organ injury and morbidity
  • Original animal- or human-based investigative papers or state-of-the-art review papers examining the contribution of the circadian clock and its outputs on metabolism and immunity are sought

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/isd/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 343265
  • - Editorial

Inflammation in Sleep Debt and Sleep Disorders

Leila Kheirandish-Gozal | David Gozal | Jean-Louis Pépin
  • Special Issue
  • - Volume 2015
  • - Article ID 539627
  • - Research Article

Excessive Daytime Sleepiness Is Associated with Changes in Salivary Inflammatory Genes Transcripts

Matthew S. Thimgan | Cristina Toedebusch | ... | Paul J. Shaw
  • Special Issue
  • - Volume 2015
  • - Article ID 815721
  • - Review Article

OSAS-Related Inflammatory Mechanisms of Liver Injury in Nonalcoholic Fatty Liver Disease

Elena Paschetta | Paola Belci | ... | Valerio Nobili
  • Special Issue
  • - Volume 2015
  • - Article ID 620258
  • - Research Article

Toll-Like Receptor-4 Mediated Inflammation Is Involved in the Cardiometabolic Alterations Induced by Intermittent Hypoxia

Laureline Poulain | Vincent Richard | ... | Claire Arnaud
  • Special Issue
  • - Volume 2014
  • - Article ID 354279
  • - Review Article

Pathogenic Roles of the Carotid Body Inflammation in Sleep Apnea

Man Lung Fung
  • Special Issue
  • - Volume 2014
  • - Article ID 423120
  • - Research Article

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

Marie Joyeux-Faure | Renaud Tamisier | ... | Jean-Louis Pepin
  • Special Issue
  • - Volume 2014
  • - Article ID 146893
  • - Clinical Study

Inflammation and Growth in Young Children with Obstructive Sleep Apnea Syndrome before and after Adenotonsillectomy

Yuval Nachalon | Neta Lowenthal | ... | Aviv D. Goldbart
  • Special Issue
  • - Volume 2014
  • - Article ID 605280
  • - Clinical Study

Inflammatory Markers and Obstructive Sleep Apnea in Obese Children: The NANOS Study

Alex Gileles-Hillel | María Luz Alonso-Álvarez | ... | David Gozal
  • Special Issue
  • - Volume 2014
  • - Article ID 568951
  • - Research Article

Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction

Izolde Bouloukaki | Vaios Papadimitriou | ... | Sophia E. Schiza
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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