Mediators of Inflammation

Macrophage-Mediated Inflammatory Disorders


Publishing date
01 Feb 2013
Status
Published
Submission deadline
14 Sep 2012

Lead Editor

1Department of Orthopedics, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan

2Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 704, Taiwan

3Department of Pharmacology, The University of Texas Health Science Center, San Antonio, TX 78229-3900, USA


Macrophage-Mediated Inflammatory Disorders

Description

Mediators of macrophage-induced inflammation are critical for a variety of human inflammatory disorders, such as sepsis-related multiple organ dysfunction/multiple organ failure, microbial infection, acute brain, lung, hepatic, renal injuries, neurodegenerative disorders, tumorigenesis, osteoporosis/osteonecrosis, cardiovascular and metabolic diseases, and autoimmune diseases. Most of these cases are proinflammatory and pathogenic for disease progression once the activated macrophages actively secrete and cause an imbalance of cytokines, chemokines, and inflammation mediators. For inflammation resolution, anti-inflammatory cytokines such as interleukin-10 and transforming growth factor-β are also regulated for macrophage activation to repair the inflammatory insults. In addition to secreting mediators of inflammation, macrophage-mediated phagocytosis is generally involved not only for inflammation but also anti-inflammation.

The primary focus of this special issue will be on the current and updated knowledge of macrophage-mediated inflammatory disorders, particularly on the pathogenesis of the macrophage activation, mediators of inflammation and anti-inflammation, and strategies against such effects. In this special issue, both reviews and original research articles are welcomed. Moreover, papers showing novel methods for detecting macrophage activation and differentiation would be of great interest. Potential topics include, but are not limited to:

  • Macrophages in infection and immunity
  • Macrophages in acute brain, lung, hepatic, renal injuries, and autoimmunity
  • Macrophage/microglia in neurodegenerative disorders
  • Tumor-associated macrophages in tumorigenesis
  • Macrophages in inflammatory/autoimmune musculoskeletal diseases
  • Macrophages in cardiovascular disorders and metabolic diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 316482
  • - Editorial

Macrophage-Mediated Inflammatory Disorders

I-Ming Jou | Chiou-Feng Lin | ... | Sung-Jen Wei
  • Special Issue
  • - Volume 2013
  • - Article ID 831387
  • - Review Article

Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease

Andrzej Eljaszewicz | Małgorzata Wiese | ... | Wojciech Zegarski
  • Special Issue
  • - Volume 2013
  • - Article ID 720689
  • - Research Article

Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection

Yu-Tzu Chang | Chia-Ling Chen | ... | Yee-Shin Lin
  • Special Issue
  • - Volume 2013
  • - Article ID 942375
  • - Review Article

Role of Macrophages in the Pathogenesis of Atopic Dermatitis

Sadaf Kasraie | Thomas Werfel
  • Special Issue
  • - Volume 2013
  • - Article ID 769214
  • - Review Article

Macrophage Heterogeneity in Respiratory Diseases

Carian E. Boorsma | Christina Draijer | Barbro N. Melgert
  • Special Issue
  • - Volume 2013
  • - Article ID 632049
  • - Research Article

Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma

Christina Draijer | Patricia Robbe | ... | Barbro N. Melgert
  • Special Issue
  • - Volume 2013
  • - Article ID 328797
  • - Research Article

Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism

L. Di Cesare Mannelli | G. D'Agostino | ... | A. Calignano
  • Special Issue
  • - Volume 2013
  • - Article ID 512978
  • - Research Article

Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke

Ying-Sheng Lee | Chung-Ching Chio | ... | Kuen-Jer Tsai
  • Special Issue
  • - Volume 2013
  • - Article ID 391984
  • - Review Article

Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases

Yuki Murakami | Masato Hoshi | ... | Kuniaki Saito
  • Special Issue
  • - Volume 2013
  • - Article ID 491497
  • - Review Article

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

Yacine Kharraz | Joana Guerra | ... | Pura Muñoz-Cánoves
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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