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Inflammatory Mediators of Angiogenesis

Call for Papers

A growth of any tissues and organs is dependent on oxygen and nutrients supply via blood vessels network. Blood vessels can be formed de novo from angioblasts precursors (vasculogenesis), which is observed during fetal development, or they can sprout from preexisting vessels and then be remodeled into arteries or veins (angiogenesis). In adults, “physiological” angiogenesis is important in wound healing or a formation of corpus luteum, but inappropriate vessels growth can be observed in many pathologic conditions, during neoplasms growth, inflammatory disorders, and retina disorders, particularly coexisting with diabetes. Inflammatory process, defined as a release of mediators from activated neutrophils, macrophages, and other myeloid cells, seems to be one of the puzzle elements in angiogenesis and understanding of the possible pathways of these mediators would be helpful in the development of treatment methods. We invite authors to submit original research and review articles that seek to define the relationship between inflammation process and angiogenesis.

We are interested in articles that describe basic mechanism underlying angiogenesis, contribution of mediators with examples of physiological angiogenesis, next pathogenesis of angiogenesis both in human and using animal models, possible methods of modulation, and current concepts of treatment using anti-inflammatory agents. Potential topics include, but are not limited to:

  • Contribution of the inflammatory mediators (IMs) in blood vessels development
  • Role of coagulation system in angiogenesis
  • Identifying IMs in mechanisms of physiological angiogenesis
  • Clinical aspect of angiogenesis, for example, placental development
  • Specific features of pathological angiogenesis associated with IMs
  • Inflammatory process associated with neoplasm and angiogenesis
  • Role of inflammation in angiogenesis in the course of retinal disorders and diabetes mellitus
  • Clinical use of anti-inflammatory agents interfering with angiogenesis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Manuscript DueFriday, 15 March 2013
First Round of ReviewsFriday, 7 June 2013
Publication DateFriday, 2 August 2013

Lead Guest Editor

  • Grzegorz Szewczyk, Department of General and Experimental Pathology, Medical University of Warsaw, Krakowskie Przedmiescie 26/28, 00-927 Warsaw, Poland

Guest Editors

  • Jeffrey H. Ruth, Department of Internal Medicine, University of Michigan Medical School, 109 Zina Pitcher Drive, Ann Arbor, MI 48109, USA
  • Janusz Rak, Montreal Children's Hospital, The Research Institute of the McGill University Health Centre (RI MUHC), McGill University, Montreal, QC, Canada