Mediators of Inflammation

Anti-Inflammatory Therapy in Diabetic Retinopathy


Publishing date
03 Jan 2014
Status
Published
Submission deadline
16 Aug 2013

1Medical University of Gdansk, 80-210 Gdansk, Poland

2Dubrovnik General Hospital, Dubrovnik, Croatia


Anti-Inflammatory Therapy in Diabetic Retinopathy

Description

Diabetic retinopathy (DR) has become the most frequent cause of blindness and loss of visual acuity in the developed countries, and this upward trend is continuing. Retinal vascular leakage, inflammation, and neovascularization (NV) are features of DR. Also closely linked to retinopathy are neural changes such as neuronal cell death, gliosis, microglial activation, and altered glutamate metabolism. In the 21st century, the treatment of diabetic retinopathy will become more available and efficient. Perhaps better understanding of the mechanisms of the action of pro- and anti-inflammatory mediators on endothelial cells as well as on other cells regulating angiogenesis might allow for wider introduction of therapeutic protocols. The implementation of cytokine and chemokine antagonists, growth factors in diabetic patients, will avert vascular complications in the form of retinopathy. Therapeutic success in retinopathy treatment depends on close collaboration between a diabetologist and an ophthalmologist. Papers for this special issue should maintain current research trends and concentrate on contemporary knowledge on DR inflammatory mediators and molecular mechanisms, especially signaling molecules, as well as methods used to block TNF, VEGF, and other growth factors. Potential topics include, but are not limited to:

  • Inflammation in diabetic retinopathy
  • New inflammation markers in the development of diabetic retinopathy
  • Neurodegeneration in diabetic retinopathy—pathomechanism and therapeutic implications
  • Retinal cell apoptosis and microvascular changes in experimental diabetics
  • The role of cytokines, chemokines, and adhesion molecules in DR
  • The diagnostic function of optical coherent tomography (OCT) in diabetic retinopathy
  • Use of nonsteroidal anti-inflammatory drugs for DR

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/retino/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 947896
  • - Editorial

Anti-Inflammatory Therapy in Diabetic Retinopathy

Katarzyna Zorena
  • Special Issue
  • - Volume 2014
  • - Article ID 492926
  • - Review Article

Current Trends in the Monitoring and Treatment of Diabetic Retinopathy in Young Adults

Dorota Raczyńska | Katarzyna Zorena | ... | Bartosz L. Sikorski
  • Special Issue
  • - Volume 2014
  • - Article ID 131538
  • - Clinical Study

Effect of the Administration of Alpha-Lipoic Acid on Contrast Sensitivity in Patients with Type 1 and Type 2 Diabetes

Anna Gębka | Ewelina Serkies-Minuth | Dorota Raczyńska
  • Special Issue
  • - Volume 2013
  • - Article ID 913754
  • - Research Article

Evaluation of Corneal Endothelium in Children and Adolescents with Type 1 Diabetes Mellitus

Beata Urban | Dorota Raczyńska | ... | Małgorzata Krętowska
  • Special Issue
  • - Volume 2013
  • - Article ID 818671
  • - Clinical Study

Inflammation, Haemostatic Disturbance, and Obesity: Possible Link to Pathogenesis of Diabetic Retinopathy in Type 2 Diabetes

Martina Tomić | Spomenka Ljubić | ... | Tamara Poljičanin
  • Special Issue
  • - Volume 2013
  • - Article ID 434560
  • - Review Article

The Diagnostic Function of OCT in Diabetic Maculopathy

Bartosz L. Sikorski | Grazyna Malukiewicz | ... | Dorota Raczynska
  • Special Issue
  • - Volume 2013
  • - Article ID 986217
  • - Clinical Study

Gene Expression of IGF1, IGF1R, and IGFBP3 in Epiretinal Membranes of Patients with Proliferative Diabetic Retinopathy: Preliminary Study

Dorota Romaniuk | Malgorzata W. Kimsa | ... | Urszula Mazurek
  • Special Issue
  • - Volume 2013
  • - Article ID 510451
  • - Research Article

Poly (ADP-Ribose) Polymerase Mediates Diabetes-Induced Retinal Neuropathy

Ghulam Mohammad | Mohammad Mairaj Siddiquei | Ahmed M. Abu El-Asrar
  • Special Issue
  • - Volume 2013
  • - Article ID 436329
  • - Clinical Study

Body Mass Index: A Risk Factor for Retinopathy in Type 2 Diabetic Patients

Snježana Kaštelan | Martina Tomić | ... | Mirela Karabatić
  • Special Issue
  • - Volume 2013
  • - Article ID 274726
  • - Clinical Study

Plasma Levels of IL-17, VEGF, and Adrenomedullin and S-Cone Dysfunction of the Retina in Children and Adolescents without Signs of Retinopathy and with Varied Duration of Diabetes

Kornel Semeran | Przemysław Pawłowski | ... | Artur Bossowski
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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