Metabolic disorders are a group of diseases that affect metabolic processes and include dyslipidaemia, atherosclerosis, obesity, hypertension, diabetes, osteoporosis, gout, fatty liver, and metabolic syndrome. There is increasing evidence to show that inflammation plays an important role in the pathogenesis of metabolic disorders, such as abnormal glucose tolerance caused by adipose tissue inflammation and autoimmune response, gout caused by monosodium urate-induced inflammation, osteoporosis caused by inflammation of rheumatic diseases, or non-alcoholic fatty liver disease.

Previous studies have shown that inflammation induced by the innate and adaptive immune system has a critical role in metabolic disorders, although the mechanism by which these immune cells and their cytokines affect the development of these diseases is still unclear. Furthermore, many drugs for the treatment of metabolic diseases have anti-inflammatory effects. Therefore, knowledge of the role of inflammation in the development of metabolic disorders has the potential to lead to significant clinical benefit.

This Special Issue aims at furthering our understanding of inflammatory regulation in metabolic diseases. We invite authors to contribute original research articles as well as review articles that focus on the topic of inflammatory regulation in metabolic dysfunction.

Potential topics include but are not limited to the following:

• Basic molecular and cellular mechanisms regulating inflammation in metabolic disorders
• Innate and adaptive immune responses in metabolism
• Inflammatory markers in metabolic disorders
• Identification and validation of novel agents that modulate inflammatory responses in metabolic diseases
• Therapeutics targeting inflammation and metabolic diseases
• Novel inflammatory-related agents and technologies with potential applications in the diagnosis and treatment of metabolic diseases