Mediators of Inflammation

Mediators of Inflammation in Pulmonary Diseases


Status
Published

1University of Patras, Patras, Greece

2University of Crete, Heraklion, Greece

3Hospital Universitari Vall d’Hebron, Barcelona, Spain

4Università degli studi di Milano, Milan, Italy


Mediators of Inflammation in Pulmonary Diseases

Description

Inflammation is supposed to play a great role in the pathogenesis of nearly all the most common diseases of the respiratory system. In bronchial asthma there are numerous proinflammatory mediators that are responsible for the onset and the progression of the disease. Moreover, in chronic obstructive pulmonary disease (COPD), that is, a major cause of morbidity and mortality all around the world, cigarette smoke mainly causes the initiation of the inflammatory process that leads to an impaired respiratory function. Sleep disturbances, including sleep apnea, can lead to a chronic inflammation provoked by intermittent hypoxia that may cause endothelial dysfunction and increase the risk of coronary artery disease, hypertension, and even diabetes. Finally, pulmonary infections result in the orchestration of an inflammatory process that targets the causative agent in order to protect the host.

We particularly take an interest in manuscripts that clearly show the relationship between chronic tissue inflammation and the obstructive diseases of the airways, including bronchial asthma and chronic obstructive pulmonary disease. Original research articles as well as reviews that summarize our current knowledge and demonstrate future perspectives on controlling inflammation using standard or novel diagnostic and therapeutic techniques are welcome. Moreover, papers dealing with the role of endothelial dysfunction in obstructive sleep apnea would be of great interest. Finally, manuscripts that discuss inflammatory process caused by infections of the respiratory system cannot be missing from this special issue. The immune response that takes place is crucial and should be well described.

Potential topics include, but are not limited to:

  • Inflammation in COPD
  • Mediators of inflammation in bronchial asthma
  • Inflammatory pathways in sleep apnea
  • Pulmonary infections and inflammatory response
  • Respiratory infections that cause exacerbations of asthma/COPD
  • Similarities and differences between inflammatory and infectious diseases of the lung

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 364758
  • - Research Article

A Subgroup of Latently Mycobacterium tuberculosis Infected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens

Ralf Baumann | Susanne Kaempfer | ... | Gerhard Walzl
  • Special Issue
  • - Volume 2015
  • - Article ID 739219
  • - Editorial

Mediators of Inflammation in Pulmonary Diseases

Kostas Spiropoulos | Nikolaos Siafakas | ... | Kiriakos Karkoulias
  • Special Issue
  • - Volume 2015
  • - Article ID 258168
  • - Research Article

γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation

Weixi Zhang | Xueya Zhang | ... | Changchong Li
  • Special Issue
  • - Volume 2015
  • - Article ID 862086
  • - Research Article

Serum Vitamin A and Inflammatory Markers in Individuals with and without Chronic Obstructive Pulmonary Disease

L. M. O. Caram | R. A. F. Amaral | ... | I. Godoy
  • Special Issue
  • - Volume 2015
  • - Article ID 124762
  • - Research Article

Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response

Agnieszka Krupa | Marek Fol | ... | Anna K. Kurdowska
  • Special Issue
  • - Volume 2015
  • - Article ID 176926
  • - Research Article

Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice

Revathee Rajajendram | Chau Ling Tham | ... | Daud Ahmad Israf
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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