Mediators of Inflammation

Mediators of Allergic Asthma and Rhinosinusitis


Status
Published

Lead Editor

1Inha University College of Medicine, Incheon, Republic of Korea

2Jikei University School of Medicine, Tokyo, Japan

3China Medical University, Wufeng, Taiwan


Mediators of Allergic Asthma and Rhinosinusitis

Description

The pathophysiologic mechanism of allergic asthma and rhinosinusitis is so complicated and involves thousands of inflammatory mediators. They are world-wide health problems, with their steadily increasing prevalence and their negative impact on quality of life. In spite of many studies throughout the world, there are still many more pathophysiologic mechanisms to be uncovered and current mainstream of medication still remains for symptom control including bronchodilators such as β2 agonists, inhaled and systemic corticosteroid, antihistamines, and leukotriene modifiers, all only with transient symptomatic relief. Therefore, we should focus on novel mechanism and mediators so that we could better understand and cure allergic asthma and rhinosinusitis.

There are a number of topics related to pathophysiologic mechanisms. For example, we could focus on innate immunity (such as Toll-like receptors) and humoral immunity (such as immunoglobulins, cytokines, and chemokines). We could also study genetic change, upregulation or suppression of some specific genes, and their correlation with phenotypes.

If you are performing researches about these or similar topics about allergic asthma and/or rhinosinusitis, publishing your result and communicating your opinion through Mediators of Inflammation could be a great chance to announce your valuable work.

Therefore, we cordially invite you to contribute original research articles as well as review articles that will elucidate the pathophysiologic mechanisms and potential mediators related with allergic asthma and rhinosinusitis through laboratory and/or clinical studies using cell lines, laboratory animals, and human beings.

Potential topics include but are not limited to the following:

  • Innate immunity associated with allergic asthma and rhinosinusitis
  • Cytokines and chemokines associated with allergic asthma and rhinosinusitis
  • Laboratory/clinical studies to elucidate pathophysiologic mechanisms
  • Genetic variation and/or mutation associated with pathophysiology
  • Therapeutic effect and mechanism of new, novel agents

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 7405245
  • - Editorial

Mediators of Allergic Asthma and Rhinosinusitis

Young Hyo Kim | Tsuguhisa Nakayama | Da-Tian Bau
  • Special Issue
  • - Volume 2017
  • - Article ID 5675029
  • - Research Article

Neutrophil Extracellular DNA Traps Induce Autoantigen Production by Airway Epithelial Cells

Youngwoo Choi | Le Duy Pham | ... | Hae-Sim Park
  • Special Issue
  • - Volume 2017
  • - Article ID 3908049
  • - Research Article

IL-25 Could Be Involved in the Development of Allergic Rhinitis Sensitized to House Dust Mite

Dae Woo Kim | Dong-Kyu Kim | ... | Ji-Hun Mo
  • Special Issue
  • - Volume 2017
  • - Article ID 6827194
  • - Research Article

Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures

Jarline Encarnación-Medina | Rosa I. Rodríguez-Cotto | ... | Braulio Jiménez-Vélez
  • Special Issue
  • - Volume 2017
  • - Article ID 8160148
  • - Review Article

Potential Biomarkers for NSAID-Exacerbated Respiratory Disease

Hanki Park | Youngwoo Choi | ... | Hae-Sim Park
  • Special Issue
  • - Volume 2017
  • - Article ID 6249685
  • - Research Article

MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression

Aijun Jia | Yueling Wang | ... | Xudong Xiang
  • Special Issue
  • - Volume 2017
  • - Article ID 8123281
  • - Research Article

Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway

Heung-Man Lee | Ju-Hyung Kang | ... | Il-Ho Park
  • Special Issue
  • - Volume 2017
  • - Article ID 3549375
  • - Research Article

A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics

Sailesh Palikhe | Udval Uuganbayar | ... | Seung-Hyun Kim
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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