Mediators of Inflammation

Immune-Endocrine Cross-Talk in Reproductive Biology and Pathology


Publishing date
28 Mar 2014
Status
Published
Submission deadline
08 Nov 2013

1Institute of Animal Reproduction and Food Research of PAS, 10-748 Olsztyn, Poland

2Technical University of Lisbon, 1349-055 Lisbon, Portugal

3Institute of Immunology and Experimental Therapy of PAS, 53-114 Wrocław, Poland


Immune-Endocrine Cross-Talk in Reproductive Biology and Pathology

Description

Immune cells products, that is, cytokines, chemokines, eicosanoids, and nitric oxide, primarily participate in host responses to disease or infection but are also involved in homeostatic mechanisms in the reproductive tract. The physiological function of the reproductive tract is dependent on a cross-talk between immune-endocrine factors. Although, the importance of cytokines and other inflammatory mediators on physiological homeostasis in reproductive tract is unique, the molecular, receptor, intra- and intercellular mechanisms mediating immune-endocrine cross-talk are still unknown. Moreover, the mechanism by which the fetal allograft is tolerated by the maternal immune system is still a mystery.

To promote discussion and further development in this exciting area of research, we invite investigators to contribute with original research articles, as well as review articles, that seek to elucidate the role of inflammatory mediators and immune mechanisms of inter- and intraorgan communications within the reproductive tract. We are interested in articles that describe basic mechanisms underlying the contribution of inflammatory mediators to physiological reproductive processes and to the pathogenesis of reproductive disorders and infertility, both in human and other species by using animal models. These articles will also address possible new methods of diagnosis and current concepts of treatment using anti-inflammatory and immune-modulating agents. Potential topics include, but are not limited to:

  • Cytokines and other inflammatory mediators on the central regulation of reproductive processes
  • Cytokines and chemokines as local regulators of the estrous cycle and pregnancy
  • Sex steroids modulatory effects on immune system
  • Immunological regulation of embryo/fetal-maternal cross-talk including the role of antigen presenting molecules
  • Immune regulated aspects of male reproduction and contraception
  • Lipid mediators in physiology and pathology of reproduction
  • Glucocorticoids in physiology and pathology of reproduction
  • Nitric oxide and other angiogenic factors in physiology and pathology of reproduction
  • Cytokines and other inflammatory mediators effects on cell biology, especially on different cell death modalities and cell-to-cell communication
  • Inflammatory processes in the uterus
  • Inflammatory mediators and carcinogenesis in the reproductive tract

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/ict/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 856465
  • - Editorial

Immune-Endocrine Cross-Talk in Reproductive Biology and Pathology

António M. Galvão | Graça M. Ferreira-Dias | ... | Dariusz J. Skarżyński
  • Special Issue
  • - Volume 2014
  • - Article ID 579279
  • - Review Article

Major Histocompatibility Complex I Mediates Immunological Tolerance of the Trophoblast during Pregnancy and May Mediate Rejection during Parturition

Anna Rapacz-Leonard | Małgorzata Dąbrowska | Tomasz Janowski
  • Special Issue
  • - Volume 2014
  • - Article ID 397815
  • - Clinical Study

Low Intraprostatic DHT Promotes the Infiltration of CD8+ T Cells in BPH Tissues via Modulation of CCL5 Secretion

Yu Fan | Shuai Hu | ... | Jie Jin
  • Special Issue
  • - Volume 2014
  • - Article ID 769239
  • - Research Article

CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4+ T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice

Tomasz Maj | Anna Slawek | Anna Chelmonska-Soyta
  • Special Issue
  • - Volume 2014
  • - Article ID 839290
  • - Research Article

Metalloprotease Dependent Release of Placenta Derived Fractalkine

Monika Siwetz | Astrid Blaschitz | ... | Martin Gauster
  • Special Issue
  • - Volume 2014
  • - Article ID 649702
  • - Review Article

Lysophosphatidic Acid (LPA) Signaling in Human and Ruminant Reproductive Tract

Izabela Wocławek-Potocka | Paulina Rawińska | ... | Dariusz Jan Skarzynski
  • Special Issue
  • - Volume 2014
  • - Article ID 635364
  • - Research Article

Bisphenol A Alters -hCG and MIF Release by Human Placenta: An In Vitro Study to Understand the Role of Endometrial Cells

C. Mannelli | F. Ietta | ... | Luana Paulesu
  • Special Issue
  • - Volume 2014
  • - Article ID 692067
  • - Review Article

A Role of Lipid Metabolism during Cumulus-Oocyte Complex Maturation: Impact of Lipid Modulators to Improve Embryo Production

E. G. Prates | J. T. Nunes | R. M. Pereira
  • Special Issue
  • - Volume 2014
  • - Article ID 248963
  • - Research Article

The First Trimester Gravid Serum Regulates Procalcitonin Expression in Human Macrophages Skewing Their Phenotype In Vitro

Damiano Rami | Martina La Bianca | ... | Roberta Bulla
  • Special Issue
  • - Volume 2014
  • - Article ID 208103
  • - Research Article

Interleukins Affect Equine Endometrial Cell Function: Modulatory Action of Ovarian Steroids

Anna Z. Szóstek | Antonio M. Galvão | ... | Dariusz J. Skarzynski
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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