Research Article

Complications, Not Minimally Invasive Surgical Technique, Are Associated with Increased Cost after Esophagectomy

Table 1

Overview of study population.

Median (IQR) or frequency (%) value
AllTHEOpenHybridMIE

Patient variables

(%)80 (100)11 (13.75)11 (13.75)41 (51.25)17 (21.25)

Age65.2 (59.6−75.3)67.4 (60.4−76.2)65.1 (59.7−75.6)64.7 (56.8−75.4)63.4 (59.5−73.8)0.891

Gender0.241
 Male59 (73.8)10 (90.9)6 (54.6)29 (70.7)14 (82.4)
 Female21 (26.2)1 (9.1)5 (45.5)12 (29.3)3 (17.7)

Preoperative comorbidities or treatments
 Hypertension44 (55.0)4 (36.4)6 (54.6)25 (61.0)9 (52.9)0.550
 CAD15 (18.8)4 (36.4)1 (9.1)7 (17.1)3 (17.7)0.502
 Prior CTS11 (13.8)1 (9.1)2 (18.2)6 (14.6)2 (11.8)1.000
 Preop XRT51 (63.8)7 (63.6)5 (45.5)29 (70.7)10 (58.8)0.455
 Preop Chemo52 (65.0)7 (63.6)6 (54.6)29 (70.7)10 (58.8)0.729
 COPD10 (12.5)1 (9.1)2 (18.2)5 (12.2)2 (11.8)0.955
 CHF5 (6.3)2 (18.2)1 (9.1)2 (4.9)0 (0.0)0.189
 Diabetes16 (20.0)2 (18.2)1 (9.1)9 (22.0)4 (23.5)0.904

Zubrod class0.851
 Normal Activity33 (41.3)5 (45.5)4 (36.4)15 (36.6)9 (52.9)
 Symptomatic47 (58.8)6 (54.6)7 (63.6)26 (63.4)8 (47.1)

ASA class0.573
 II7 (8.8)2 (18.2)0 (0.0)4 (9.8)1 (5.9)
 III69 (86.3)9 (81.8)11 (100.0)33 (80.5)16 (94.1)
 IV4 (5.0)0 (0.0)0 (0.0)4 (9.8)0 (0.0)

Operative outcomes

OR time (min)441 (399−511)330 (307−348)449 (397−486)437 (410−480)527 (461−581)<0.001

LOS (days)8 (7−9)7 (7−12)8 (7−13)8 (7−9)7 (6−9)0.476

Postoperative complications42 (52.5)5 (45.5)5 (45.5)23 (56.1)9 (52.9)0.912

Data presented as (%) for categorical variables or median (interquartile range) for continuous variables.
p values indicate Fisher’s Exact test for categorical variables and Kruskal-Wallis one-way test analysis of variance for continuous variables.
IQR: interquartile range. THE: transhiatal esophagectomy. MIE: minimally invasive esophagectomy. Preop: preoperative. CAD: coronary artery disease. CTS: cardiothoracic surgery. XRT: radiotherapy. COPD = chronic obstructive pulmonary disease. CHF: congestive heart failure. ASA: American Society of Anesthesiologist. LOS: length of stay.