Spinal Biologics in Minimally Invasive Lumbar Surgery
Table 1
Fusion rates for various bone grafts in posterior approaches to minimally invasive interbody fusions.
Bone grafts material
Posterior approaches to MIS interbody fusion
Number of studies
Number of patients
Fusion rate (%)
Range (%)
Autograft (local and iliac crest)
2
29
86
83–91
Autograft (local) alone
23
1209
91
68–100
Autograft (iliac crest) alone
3
101
90–100
Autograft + allograft
5
178
92–100
BMA (as extender)
2
109
93-94
DBM (as extender)
5
264
85
77–97
Ceramics (as extender)
3
217
86
83–88
Ceramics alone
1
57
76
76
rhBMP-2 (with another bone graft)
7
486
65–100
rhBMP-2 alone
1
36
94
are no significant differences in fusion rates among these groups; however, they do demonstrate significantly higher fusion rates when compared to the rest ().