Application of Dynamic 18F-FDG PET/CT for Distinguishing Intrapulmonary Metastases from Synchronous Multiple Primary Lung Cancer
Table 4
Individual results in the IPM group.
Patient no.
Location of primary tumor
Pathological type
8th TNM stage
(cm)
SUVmax-pt
(min-1)
Location of metastatic tumor
(cm)
SUVmax-mt
(min-1)
1
RCLC
AC
cT2bN3M1c, IVB
4.80
7.70
0.0375
LUL
0.60
1.05
0.0036
0.15
0.0019
2
LUL
AC
cT4N2M1c, IVB
1.90
8.71
0.0687
LLL
0.70
5.24
0.0339
2.91
0.0122
3
RLL
AC
cT1cN3M1c, IVB
2.30
16.06
0.0620
LUL
0.30
1.00
0.0012
3.65
0.0228
4
LLL
AC
cT3N2M1b, IVA
6.20
14.04
0.0612
LLL
1.00
3.29
0.0212
1.02
0.0113
5
LUL
AC
cT1bN1M1c, IVB
1.60
8.84
0.0489
RML
0.60
0.48
0.0007
4.72
0.0294
6
LUL
AC
pT3N2M1b, IVA
2.90
6.46
0.0344
LUL
1.50
1.20
0.0020
1.43
0.0105
7
RCLC
AC
pT2aN3M1c, IVB
3.80
5.05
0.0263
RLL
4.00
5.52
0.0316
0.05
0.0010
8
LLL
NSCLC
cT4N3M1c, IVB
4.80
8.68
0.0458
LUL
1.30
4.51
0.0201
1.66
0.0060
9
LUL
Poorly differentiated carcinoma
cT4N3M1a, IVA
7.60
11.11
0.0556
RUL
2.50
9.47
0.0411
2.33
0.0091
10
LLL
AC
cT4N3M1c, IVB
5.80
8.06
0.0611
LUL
0.40
0.61
0.0014
0.13
0.0069
11
LCLC
AC
cT4N2M1a, IVA
8.80
7.89
0.0471
LLL
4.80
5.80
0.0341
0.31
0.0018
12
RCLC
SCC
cT2aN3M1b, IVA
3.90
7.26
0.0453
RUL
1.40
0.96
0.0039
1.17
0.0088
13
RLL
Invasive AC, acinar
pT1cN3M1c, IVB
3.00
10.22
0.0499
LUL
1.80
0.43
0.0002
3.17
0.0165
14
RUL
Lung cancer
cT3N3M1c, IVB
4.10
13.85
0.0551
RUL
0.50
0.60
0.0007
2.17
0.0120
15
RUL
Invasive AC, papillary
pT4N2M1a, IVA
2.20
4.98
0.0289
RLL
0.50
0.75
0.0009
0.77
0.0113
16
RML
AC
pT4N2M1b, IVA
3.30
9.49
0.0423
RLL
0.40
0.64
0.0003
1.27
0.0122
17
RCLC
AC
pT2bN1M1a, IVA
4.40
13.69
0.0756
LUL
1.10
2.28
0.0081
1.04
0.0099
18
RML
SCC
cT4N3M1a, IVA
4.90
9.79
0.0547
RLL
0.50
0.37
0.0011
1.26
0.0090
19
RML
AC
cT4N3M1c, IVB
6.00
6.97
0.0381
RUL
1.40
1.59
0.0065
0.03
0.0017
20
LLL
SCC
cT3N1M0, IIIA
5.00
9.85
0.0535
LLL
1.50
6.71
0.0359
2.50
0.0132
21
RLL
Invasive AC, acinar
pT4N0M0, IIIA
1.80
1.33
0.0042
RUL
0.30
0.43
0.0006
0.68
0.0004
22
LUL
Invasive AC, acinar
pT4N2M0, IIIB
2.80
9.26
0.0497
LLL
0.40
0.14
0.0002
2.96
0.0174
23
RLL
AC
cT4N2M0, IIIB
1.80
6.28
0.0327
RUL
0.50
0.59
0.0010
2.31
0.0161
24
RUL
AC
cT1cN3M1c, IVB
1.60
6.35
0.0413
LLL
2.50
6.88
0.0456
1.22
0.0076
Median (min–max)
1.27 (0.03-4.72)
0.0102 (0.0004-0.0294)
IPM: intrapulmonary metastases; : largest diameter of primary tumor; : largest diameter of metastatic tumor; : influx rate constant; SUVmax: maximum standardized uptake value; SUVmax-pt: SUVmax of primary tumor; SUVmax-mt: SUVmax of metastatic tumor; :Ki of primary tumor; : of metastatic tumor; : absolute difference between and ;: absolute difference between and ; RUL: right upper lobe; RML: right middle lobe; RLL: right lower lobe; LUL: left upper lobe; LLL: left lower lobe; RCLC: right central lung cancer; LCLC: left central lung cancer; AC: adenocarcinoma; SCC: squamous cell carcinoma; NSCLC: non-small cell lung cancer.
